Doctor Patel in the lab

Renal Pathology


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ProPath’s Renal Pathology division serves nephrologists, transplant surgeons and others caring for patients with renal disease by providing expert renal biopsy interpretation and unmatched patient-centered service.

The Renal Pathology division will provide the following:

  • Comprehensive diagnostic tissue interpretation including light microscopy, immunofluorescence and electron microscopy 
  • ProPath's state-of-the-art immunohistochemistry laboratory with diagnostic support for work on atypical lymphoid infiltrates, amyloid typing and virus detection (CMV, BKV, etc.) 
  • Experienced, board-certified pathologists with extensive expertise in native and transplant renal biopsy interpretation 
  • Rapid, 24 to 48 hour turnaround time for light microscopy, immunofluorescence and electron microscopy 
  • Emergency and weekend biopsy processing 
  • Excellent communication with nephrologist(s) 
  • All biopsy results are discussed with the nephrologist and results are correlated with clinical and laboratory information 
  • The pathologist and nephrologist may review the biopsy together via the Internet using a secure login. The nephrologist receives a comprehensive report incorporating the diagnosis with clinical and laboratory information and biopsy images 
  • A Renal Biopsy Kit with everything needed to submit specimens for testing is provided



Donna J. Lager, M.D., is the Director of ProPath Renal Pathology and is board-certified in anatomic and clinical pathology. She is a graduate of the University of Iowa College of Medicine in Iowa City, Iowa. She completed a transitional internship at Tucson Medical Center in Tucson, Arizona, and returned to the University of Iowa where she completed her residency in anatomic and clinical pathology, followed by a fellowship in surgical/renal pathology. She joined the faculty of the Department of Pathology at the University of Iowa and, in 1997, moved to the Mayo Clinic in Rochester, Minnesota. Under her leadership, the Mayo Clinic Renal Biopsy service grew to become one of the largest in the world. Dr. Lager has been active in medical student and resident/fellow education. She has more than 75 peer reviewed publications, book chapters and abstracts and has lectured both nationally and internationally on native renal disease and renal transplant pathology. Dr. Lager also has subspecialty interests in heart transplant pathology, gastrointestinal pathology and urologic pathology. She joined ProPath in 2009.

Dr. Lager is the co-editor of Practical Renal Pathology, A Diagnostic Approach, a volume in the Pattern Recognition series.